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Hydroxyphenyl Propamidobenzoic Acid, also known as 2-(3-(4-hydroxyphenyl)propanamido)benzoic acid, are compounds with a wide range of biological activities, primarily derived from the active constituents of oats (Avena Sativa). Dihydro-Oat alkaloids have multiple effects such as antihistamine, antioxidant, anti-irritant, anti-inflammatory, and erythema improvement. It is widely used to relieve itching, irritation, and redness of sensitive skin in areas such as medicine and cosmetics.
Product Details
CAS Number |
697235-49-7 |
Density |
1.354±0.06 g/cm3 (Predicted) |
Molecular Formula |
C16H15NO4 |
Molecular Weight |
285.29 |
Melting Point |
590.0±40.0 ℃ (Predicted) |
Boiling Point |
N/A |
Solubleness |
86.5mg/L at 20℃ |
Test Method |
HPLC |
►Anti-inflammatory and antipruritic: Dihydro-Oat Alkaloids can inhibit the degradation of keratinized cell nuclear factor NF-κB-α, which is directly related to the occurrence of inflammation, and prevent the phosphorylation of p65 protein subunit on the cellular nuclear factor NF-κB, thus blocking the process of cellular inflammation. At the same time, it reduces the occurrence of inflammatory immune response and the response of cutaneous neurodermatitis.
►Antihistamine: 2-(3-(4-hydroxyphenyl)propanamido)Benzoic Acid have antihistamine activity and can inhibit histamine signaling, resulting in anti-inflammatory and anti-itch effects.
►Antioxidant and anti-irritant: Hydroxyphenyl propamidobenzoic acid also exert antioxidant and anti-irritant effects, helping to protect the skin from environmental damage.
Areas of application
►Pharmaceutical field: Hydroxyphenyl propamidobenzoic acid can be used as anti-inflammatory and anti-itching agents in various skin creams to treat neurodermatitis, eczema and other diseases.
►Cosmetic field: Dihydro oat alkaloids are also more and more widely used in cosmetic field, it can relieve skin erythema and private parts itching problems, soothe head itching. It is used in toiletries, after-sun repair products and skin care products.
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