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Ursolic acid powder is a triterpenoid compound that exists in natural plants. It has various biological effects such as sedative, anti-inflammatory, and antibacterial. Ursolic acid also has obvious antioxidant functions, so it is widely used as medicine and Cosmetic raw materials. In addition, ursolic acid can inhibit a variety of cancers. It has great potential to become a new anti-cancer drug with low toxicity and high efficiency. KINTAI is a professional manufacturer and supplier of Ursolic Acid Powder. We mainly manufacture 98% Ursolic Acid Powder.
CAS Number | 77-52-1 | Density | 1.0261 (rough estimate) |
Molecular Formula | C30H4803 | Molecular Weight | 456.71 |
Melting Point | 292 ℃(dec.)(lit.) | Boiling Point | 502.79 ℃ (rough estimate) |
Storage Condition | 2-8 ℃ | Solubleness | Still soluble in methanol, acetone, pyridine, insoluble in water and petroleum ether. |
Product Name | Extract sources | CAS |
Ursolic Acid Powder | Loquat Leaf |
77-52-1 |
Non-Irradiated / Non-ETO/ Treat by Heat Only / Non-GMO | ||
Analysis Items | Specification | Test Method |
Assay | 98% Ursolic Acid | HPLC |
Physical and chemical properties | ||
Appearance | White Powder | Visual |
Odour | Characteristic | Organoleptic |
Particle Size | ≥95% Through 80 mesh | Ch.P.C.Rule47 |
Ash | ≤5.0% | Ch.P.C.Rule2302 |
Loss on drying | ≤5.0% | Ch.P.C.Rule52 |
Heavy Metals | ≤10.0ppm | Atomic Absorption |
Cadmium(Cd) | ≤1.0ppm | Atomic Absorption |
Mercury(Hg) | ≤0.1ppm | Atomic Absorption |
Arsenic(As) | ≤1.0ppm | Atomic Absorption |
Lead(Pb) | ≤2.0ppm | Atomic Absorption |
Residual Solvents | ||
- Ethanol | ≤1000 PPM | Gas Chromatography |
Microbiological Quality (Total viable aerobic count) | ||
Total Plate Count,cfu/g | ≤1000 CFU/g | Ch.P.C.Rule80 |
Mold and yeast Count,cfu/g | ≤ 100 CFU/g | Ch.P.C.Rule80 |
E. coli | Negative | Ch.P.C.Rule80 |
Salmonella | Negative | Ch.P.C.Rule80 |
Staphylococcus aureus | Negative | Ch.P.C.Rule80 |
*Storage Condition: Store in tightly closed plastic bag and keep in a cool dry place. Do not freeze. Keep always from strong direct light. | ||
*Safety Precaution: Wearing of protective goggles or safety glasses is recommended.If accidentally instilled into the eyes,immediately rinse thoroughly with water and get medical care. Wash skin with soap and water upon contact. |
Preparation of Reference Solution: Accurately weigh the appropriate amount of Ursolic Acid reference product, add the mixed solution of anhydrous ethanol: ethanol (3:2) to make a solution containing 1mg per milliliter as the reference solution.
Preparation of Sample Solution: Finely weigh and pulverize 20g of gardenia (fried gardenia according to yield conversion and weighing), put it in Soxhlet extractor, add 300ml of ether to reflux extraction until colorless, recover solvent to dry, and soak the residue in petroleum ether twice, 15ml each time, about 2min, pour petroleum ether, and use anhydroethanol-ether (2: 3) slightly heated and dissolved in a 5ml bottle as a sample solution.
Determination: Accurately absorb the sample solution and the control solution 2μl, and point on the same thin layer plate. According to the above chromatographic conditions, the color is developed. λS=520nm, λR=700nm; Chemicalbook dual-wavelength reflection sawtooth scanning; SX = 3.0; Slit: 1.20mm×1.2mm; Paper speed: 20mm/min. The absorbency integral values of the sample and the control product were measured, and the content of ursolic acid was calculated.Function
Antitumous Effect: Ursolic acid can inhibit the proliferation of HL-60 cells and induce their apoptosis. It can prevent and inhibit tumor formation and growth at all stages, inhibit tumor formation and induce cancer cell differentiation.
Liver protection and anti-inflammatory: Ursolic acid has resistance to hepatocellular carcinoma in vivo and in vitro. The clinical manifestations of ursolic acid are that it can significantly and rapidly reduce alanine aminotransferase and serum aminotransferase, subside jaundice, increase appetite, resist fibrosis and restore liver function. It has the characteristics of quick effect, short course of treatment and stable effect.
Anti-oxidation: Ursolic acid has a strong antioxidant effect, which can clear free radicals, delay the rate of cell aging, and prevent chronic diseases such as cardiovascular disease. The antioxidant effect of ursolic acid has a positive effect on the human body's anti-aging, skin freckle removal, and pigment removal.
Antibacterial and antiviral: Tapondjou et al. confirmed through acetic acid twisting test and hot plate test that ursolic acid and hydroxyursolic acid have similar anti-inflammatory and antibacterial effects. Ursolic acid can inhibit the production of superoxide induced by formylmethionyl-leucyl-phenylalanine (fMLP) and arachidonic acid respectively. When ursolic acid and fMLP were added to the cell culture medium, ursolic acid inhibited the tyrosine phosphorylation of 45ku protein induced by fMLP in a dose-dependent manner. Ursolic acid also has trypanocidal activity. After incubation for 2 hours at a concentration of 2 g·L, the activity of Trypanosoma cruzi's flagellates was completely inhibited.
Cosmetics field: Ursolic acid can absorb ultraviolet rays to prevent pigmentation caused by ultraviolet radiation. It has a strong antioxidant effect and the ability to scavenge free radicals. It has a positive effect on the human body's anti-aging, skin freckle removal, and pigmentation removal.
Health Care Industry: Ursolic acid can be added to nutritional supplements as the main ingredient of health care products to improve physical health and prevent disease.
Pharmaceuticals Industry: Ursolic acid has a wide range of antitumor effects and can be used as a new anticancer drug.
At KINTAI, we understand the importance of customization. Our OEM and ODM services empower clients to create products that align seamlessly with their brand and market requirements. From formulation to packaging, we collaborate closely with our partners to bring their visions to life.
Advantage Of KINTAI
KINTAI is a professional manufacturer and supplier of Ursolic Acid Powder. We have our own research and development center, production base, and state-of-the-art equipment. With multiple patents and certifications, we guarantee the highest quality and safety of our products. We provide comprehensive OEM and ODM services, ensuring customized products and integrated solutions. With fast delivery and secure packaging, we are your trusted partner in choosing your product. For more information, please contact us at info@kintaibio.com.
Parcel and Shipping
1> 1KG/bag, 10KG/carton,25kg/drum
2> By Express: Door to door; DHL/FEDEX/EMS; 3-4DAYS; Suitable for under 50kg; high cost; easy to pick up the goods
3> By Air: Airport to Airport; 4-5 days; Suitable for more than 50kg; high cost; professional broker needed
4> By Sea: Port to Port; 15-30days; Suitable for more than 500kg; Low cost; professional broker needed
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