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Horse chestnut extract escin is a triterpenoid saponin containing ester bonds extracted from the dried mature seeds of the Aesculus plant. It is a freeze-dried sterile preparation and a natural botanical medicine. Aescin has a wide range of pharmacological activities, including anti-inflammatory, anti-edema, enhancing venous tension, inhibiting gastric acid secretion, scavenging reactive oxygen species, and combating liver damage. At present, it is mainly used in medical practice to treat chronic venous insufficiency, cerebral edema, postoperative edema and trauma recovery.
Temperature Stability | Stable up to 70°C |
pH Stability | 4 – 7 |
Suggested Use Level | 1.00% - 10.00% |
Solubility | Water Soluble |
Ionic State | Nonionic |
Compatibility | 10% of FSS Horse Chestnut Extract is compatible with up to 90% alcohol |
Formulation Guidelines | Horse Chestnut Extract can be incorporated into the aqueous phase. |
Anti-inflammatory effect: Horse chestnut extract escin can inhibit the levels of inflammatory factors such as TNF-α and IL-1β, reduce the exudation of inflammatory tissues, and reduce tissue permeability, thus showing significant anti-inflammatory effects.
Protecting blood vessel walls: It has a protective effect on vascular endothelial cells and helps maintain the integrity of blood vessel walls.
Antibacterial effect: Aescin has a certain inhibitory effect on some bacteria and fungi, and can inhibit their growth and replication.
Hypolipidemic effect: It has the effect of regulating blood lipid metabolism, which can reduce the levels of cholesterol and triglycerides in the blood, thereby preventing cardiovascular diseases.
Antioxidant effect: Escin can neutralize free radicals, reduce the damage of free radicals to cells, and fight aging to a certain extent.
Horse chestnut extract escin is mainly used to treat cerebral edema, swelling after trauma or surgery, and venous reflux disorders such as varicose veins and thrombophlebitis. In addition, it can also be used to treat neurological diseases such as facial neuritis and neural edema, as well as cerebrovascular diseases such as cerebral infarction and cerebral hemorrhage.
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KINTAI is a professional manufacturer and supplier of escin powder, We have our own research and development center, production base, and state-of-the-art equipment. With multiple patents and certifications, we guarantee the highest quality and safety of our products. We provide comprehensive OEM and ODM services, ensuring customized products and integrated solutions. With fast delivery and secure packaging, we are your trusted partner in choosing your product. For more information, please contact us at info@kintaibio.com.
1> 1KG/bag, 10KG/carton, 25kg/drum
2> By Express: Door to door; DHL/FEDEX/EMS; 3-4DAYS; Suitable for under 50kg; high cost; easy to pick up the goods
3> By Air: Airport to Airport; 4-5 days; Suitable for more than 50kg; high cost; professional broker needed
4> By Sea: Port to Port; 15-30days; Suitable for more than 500kg; Low cost; professional broker needed
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