Betulinic acid
Specification: 98% Betulinic acid （Another specification is 50% Betulinic Acid）
Appearance: White powder
CAS No: 472-15-1
Test Method: HPLC
Lead time: 1-3 days
Shelf Life: 2 years
Sample: Free sample available
Storage: Cool dry place and avoid light
Content: Vegan, Gluten-Free, Natural, Non-GMO, Non-additive
Certs: GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, HALAL
Payment: Multiple terms acceptable like T/T, LC, DA
Company Advantage:100,000 level clean production workshop, Non-additive, Non-GMO, Non-Irradiated/treat by heat only.
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
What is Betulinic Acid?
Betulinic Acid(BA) is a pentacyclic triterpenoid compound, which is widely found in the natural world, and is mainly extracted from the bark of betula alba. By modifying the chemical structure of BA, a variety of derivatives can be obtained. Studies have shown that betulinic acid has many biological activities such as anti-inflammatory, antibacterial, anti-malaria, etc. In addition, BA also has a strong toxic effect on a variety of tumors, but has no lethal effect on normal cells, which is a very valuable natural product. BA and its derivatives have shown great potential as biologics in anti-cancer and HIV treatment, and are of great value for the research and development of new drugs.
Product Details
Chemical & Physical Properties
| CAS Number | 472-15-1 | Density | 1.065±0.06 g/cm3(Predicted) |
| Molecular Formula | C30H48O3 | Molecular Weight | 456.71 |
| Melting Point | 295-298 ℃ (dec.)(lit.) | Boiling Point | 550.0±33.0 ℃(Predicted) |
| Solubleness | Soluble in DMSO (up to 25mg/ml) or ethanol (up to 25mg/ml) | Test Method | HPLC |
Product Quality Specification & Standard
|
Product name |
Betulonic Acid |
|
Extract source |
Birch bark |
|
Extraction Solvent |
Ethyl alcohol |
|
Appearance |
White powder |
|
Solubility |
Soluble in: chloroform, ethanol, acetone, methanol, ether; very slightly soluble in benzene |
|
Identification |
HPLC |
|
Ash |
NMT 0.5% |
|
Heavy metals |
NMT 20 PPM |
|
Loss On Drying |
NT 5.0% |
|
Powder size |
80Mesh, NLT90% |
|
Assay |
Min. 95.0% |
|
Residual Solvents |
|
|
- N-hexane |
NMT 290 PPM |
|
- Methanol |
NMT 3000 PPM |
|
- Acetone |
NMT 5000 PPM |
|
- Ethyl Acetate |
NMT 5000 PPM |
|
- Ethanol |
NMT 5000 PPM |
|
Pesticide Residues |
|
|
- Total DDT (Sum of p,p'-DDD,P,P'-DDE,o,p'-DDT and p,p' -DDT) |
NMT 0.05 PPM |
|
- Aldrin, Endrin, Dieldrin |
NMT 0.01 PPM |
|
Microbiological Quality (Total viable aerobic count) |
|
|
- Bacteria, CFU/g, not more than |
NMT 103 |
|
- Moulds and yeasts, CFU/g, not more than |
NMT 102 |
|
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
|
Storage |
In Tight, Light-resistant and Dry Place. Avoid Direct Sunshine. |
|
Shelf life |
2 years |
Functions
Anti-inflammatory effect: Because betulinic acid is a pentacyclic triterpenoid compound, it has anti-inflammatory activity. Betulinic acid has mild anti-inflammatory properties at higher concentrations, which have been verified in vivo and in vitro models. It can inhibit PGE2 production and reduce inflammation.
Antitumor effect: Betulinic acid, as an anticancer drug, has lower toxicity and higher tumor inhibitory activity. It was first found to have selective cytotoxicity to melanoma cells, and in recent years, it has also been found to have strong broad-spectrum activity on a variety of tumor cells. Its anti-tumor mechanism mainly includes blocking the cell cycle of tumor cells, inducing apoptosis and autophagy of tumor cells, and improving the immune function of the body.
Antiviral effect: Antiviral effect has a more prominent antiviral activity, especially anti-HIV activity, and it has an effective effect on anti-other viruses such as hepatitis C virus, spora simplex virus, Iko virus, influenza virus and so on.
Antioxidant stress activity: BA has a protective effect on normal cells and the body, which has a certain relationship with antioxidant stress. For example, betulinic acid has a protective effect on ischemia-reperfusion injury of brain, kidney and heart.
Application Fields
Betulinic acid is a natural pentacyclic triterpenoid compound with various biological activities and pharmacological effects, which has a wide application prospect in medicine, health care products and other fields.
OEM and ODM Services
As a client- centric company, KINTAI offers both OEM and ODM services. Our state- of- the- art R&D center and product base, coupled with a platoon of experts, enable us to unite with guests to develop custom products acclimatized to their specific requirements.
Certifications
Advantage Of KINTAI
Parcel and Shipping
1> 1KG/bag, 10KG/carton, 25kg/drum
2> By Express: Door to door; DHL/FEDEX/EMS; 3-4DAYS; Suitable for under 50kg; high cost;easy to pick up the goods
3> By Air: Airport to Airport; 4-5 days; Suitable for more than 50kg; high cost; professional broker needed
4> By Sea: Port to Port; 15-30days; Suitable for more than 500kg; Low cost; professional broker needed
Conclusion
In conclusion, KINTAI's Betulinic Acid stands as a pinnacle of quality and innovation in the botanical extracts market. With our dedication to excellence, numerous patents, certificates, and a robust quality system, we ensure that our customers receive not just a product but a comprehensive solution for their unique needs. For inquiries and orders, contact us at info@kintaibio.com. Choose KINTAI for a natural and effective Betula Alba Bark that exceeds expectations.
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