Pure Piperine

What is Pure Piperine?

Pure Piperine is a substance that comes from the deep layers of black pepper. 

The chemical structure of piperine belongs to the cinnamic amide class, with medium polarity and weak alkalinity. It is an alkaloid unique to piperine plants.

Piperine is relatively sensitive to light and easily decomposes into isopiperine and isopiperine when exposed to light. It is difficult to dissolve in water, easily soluble in acetic acid, and soluble in vinegar or benzene. Piperine is lipophilic, so optimal absorption is when taken with food.
Piperine has a variety of pharmacological and biological activities, and has the ability to resist tumors, lower lipids, and increase the effects of some drugs.

Specifications

Product Name	Extract sources	CAS
Pure Piperine Powder	Black pepper	94-62-2
Non-Irradiated / Non-ETO/ Treat by Heat Only / Non-GMO
Analysis Items	Specifications	Test Method
Assay	98% Piperine	HPLC
Physical and chemical properties
Appearance	White powder	Visual
Odour	Characteristic	Organoleptic
Particle Size	≥95% Through 80 mesh	Ch.P.C.Rule47
Ash	≤5.0%	Ch.P.C.Rule2302
Loss on drying	≤5.0%	Ch.P.C.Rule52
Heavy Metals	≤10.0ppm	Atomic Absorption
Cadmium(Cd)	≤1.0ppm	Atomic Absorption
Mercury(Hg)	≤0.1ppm	Atomic Absorption
Arsenic(As)	≤1.0ppm	Atomic Absorption
Lead(Pb)	≤2.0ppm	Atomic Absorption
Residual Solvents
- Ethanol	≤1000 PPM	Gas Chromatography
Microbiological Quality (Total viable aerobic count)
Total Plate Count,cfu/g	≤1000 CFU/g	Ch.P.C.Rule80
Mold and yeast Count,cfu/g	≤ 100 CFU/g	Ch.P.C.Rule80
E. coli	Negative	Ch.P.C.Rule80
Salmonella	Negative	Ch.P.C.Rule80
Staphylococcus aureus	Negative	Ch.P.C.Rule80
*Storage Condition: Store in tightly closed plastic bag and keep in a cool dry place. Do not freeze. Keep always from strong direct light.
*Safety Precaution: Wearing of protective goggles or safety glasses is recommended.If accidentally instilled into the eyes,immediately rinse thoroughly with water and get medical care. Wash skin with soap and water upon contact.

Our Advantage:

1) 11 years of rich R&D and production experience to ensure the stability of product parameters;

2) 100% plant extract, safer and healthier;

3) Professional R&D team can provide special solutions and customized services according to customer requirements;

4) Free samples can be provided.

Quality Control Measures:

Imbued in each step of piperine's creation, quality control rigorously tests every batch to exceed industry standards, guaranteeing unmatched quality, purity, and potency from the raw materials to the final product.

Mechanism of action that promotes absorption

1️⃣ Changes the absorption of nutrients through thermogenesis

A large part of the absorption and utilization of food is determined by food-induced thermogenesis, and piperine can also increase the absorption of nutrients through thermogenesis.
Piperine has thermogenic properties and can cause an increase in gastrointestinal epithelial cell bioenergetic (cAMP) processes. However, it is worth noting that the local heating effect of piperine is relatively short-lived, and the absorption of nutrients will also increase serum concentration in an instant.

2️⃣ By increasing solubility

Studies have shown that black pepper and piperine in the diet cause an increase in bile flow and at the same time reduce the effect of bile solids - hydrogenated bile; especially at low doses, the effect of black pepper is more obvious. The increase in bile acid secretion will increase the absorption of lipid nutrients.

3️⃣ By increasing blood flow

Piperine can increase blood flow in the gastrointestinal tract, thereby improving absorption and utilization.

4️⃣ By increasing the permeability of intestinal epithelial cells

Piperine can modulate membrane dynamics and increase permeability at the absorption site. Piperine stimulates the activity of γ-glutamyl transpeptidase through interaction with intestinal epithelial cells, thereby increasing the absorption of amino acids by epithelial cells.

5️⃣Changes the absorption of nutrients by inhibiting the body’s metabolic mechanism
6️⃣ By regulating gastrointestinal juice secretion and prolonging gastric emptying

Studies have shown that piperine can stimulate gastric acid secretion (increased by 22.2% to 334.6% at different concentrations of piperine), thereby promoting drug absorption.

Specific studies on nutrient absorption

Black pepper extract has been shown to increase the bioavailability of fat-soluble vitamins (beta-carotene), water-soluble vitamins (vitamin C), selenoamino acids, coenzyme Q10, resveratrol, and curcumin (Fernández-Lázaro et al., 2020 Year). The rationale is that piperine increases the serum half-life of coenzyme Q10 and beta-carotene, thereby extending their exposure time and efficacy.

Pure Piperine Functions

1. Antioxidant

Enhance antioxidant enzyme activity and inhibit lipid peroxide accumulation.

2. Anti-inflammation

Inhibit inflammatory factors, maintain immune balance, and prevent excessive differentiation of T cells.

3. Antidepressant

Regulate neurohormone levels, enhance nerve regeneration and cell protection capabilities.

4. Anti-tumor

Regulate cell growth cycle, inhibit invasion, metastasis and angiogenesis.

5. Improve metabolic syndrome

Prevent or improve hepatic steatosis and insulin resistance.

6. Protect the skeletal muscle system

Promote the differentiation of osteoblasts and promote bone mineralization.

Application Fields:

Piperine can be used in daily chemicals, health care, medicine, feed and other related products
Health products (slimming) 0.5%-1%
Cosmetics (skin tone adjustment) about 2%
Feed additives (growth, appetite, digestion, immunity and disease resistance)
(Its combination with curcumin can significantly improve the body's absorption and utilization rate of nutritional and health care products, and has a very good synergistic effect.)
According to research, adding piperine to shrimp feed can significantly improve shrimp growth, feed efficiency, dietary digestibility and non-specific immunity. In particular, piperine supplementation is a useful immunostimulant for controlling Vibrio infection, and based on our results, the optimal dose of piperine supplementation for P. vannamei feed is 1.0–2.0 g/kg.

Why choose us?

● Made in China, using home-grown raw materials to create high-quality products
● Fast delivery time
● Multiple quality control processes
● Experienced operations and quality assurance personnel
● Strict internal testing standards
● Dual warehouses in China and the United States, quick response

OEM and ODM Services:

KINTAI offers OEM and ODM services, allowing businesses to leverage the benefits of it in their unique formulations.

• OEM Services:

Original Equipment Manufacturer services enable businesses to brand the product with their identity, ensuring consistency and recognition throughout the supply chain.

• ODM Services:

ODM services enhance Dark Pepper Extract Powder's adaptability by providing flexibility in formulation and presentation to meet brand identity and consumer preferences across diverse business sectors.

FAQ

Q: Is it safe for daily consumption?

A: Daily consumption of Piperine is generally safe within recommended dosages, but consultation with a healthcare professional is advised as needed.

Q: Can it be used in cooking?

A: Piperine's concentrated form is applied primarily in supplements, not culinary settings, to enhance nutrient absorption and not as a flavor enhancer.

Q: Does it interact with medications?

A: Individuals on medication should seek professional guidance when considering adding Piperine to their routine, as it can interact with medication metabolism.

Q: What distinguishes Bioperine from regular piperine bulk powder?

A: Bioperine is a trademark for a consistent, standardized form of piperine, ensuring both purity and potency in every batch and, thus, offering a reliable and effective product.

Certificate

Advantage Of KINTAI

KINTAI is a professional manufacturer and supplier of Pure Piperine Powder, We have our own research and development center, production base, and state-of-the-art equipment. With multiple patents and certifications, we guarantee the highest quality and safety of our products. We provide comprehensive OEM and ODM services, ensuring customized products and integrated solutions. With fast delivery and secure packaging, we are your trusted partner in choosing your product. For more information, please contact us at herb@kintaibio.com.

Parcel and Shipping

1> 1KG/bag, 10KG/carton,25kg/drum

2> By Express:
Door to door;DHL/FEDEX/EMS;3-4DAYS; Suitable for under 50kg; high cost;easy to pick up the goods

3> By Air：
Airport to Airport;4-5 days;Suitable for more than 50kg;high cost;professional broker needed

4> By Sea:
Port to Port;15-30days; Suitable for more than 500kg;Low cost;professional broker needed

Contact Us

As customers increasingly seek natural and effective solutions for their health and wellness journey, Bioperine Powder by KINTAI, offers a versatile and valuable ingredient for improved nutrient absorption, metabolic support, and antioxidant properties, with the added benefit of OEM and ODM services for integrating this natural powerhouse into unique formulations, elevating products and promoting overall well-being. For inquiries about selecting the right piperine bulk powder contact us at herb@kintaibio.com.